A Power of Attorney (PoA) created in one Indian state, such as Karnataka, is generally valid for executing deeds in another state, like Goa. However, it's crucial to have the PoA validated by the Collector (JC/SDO/District Registrar) in the destination state under Section 18 of the Indian Stamp Act. This validation process ensures compliance with potential stamp duty variations between states, with any difference being levied and certified.