Tapentadol is a prescripttion opioid medication for treating specific types of moderate-to-severe pain. Physical dependence is one of the risks that might be associated with taking the drug due to its effects on the nervous system.
The medication activates mu-opioid receptors within the central nervous system. The nervous system can adapt to the effect of the drug when taken repeatedly. As a consequence, the body becomes accustomed to the effect of the drug and starts depending on it in order to operate normally.
Discontinuation of tapentadol therapy abruptly after developing physical dependence leads to withdrawal symptoms such as sweating, irritability, agitation, muscle aches, nausea, vomiting, and insomnia.
Physical dependence and addiction are different phenomena. Physical dependence is an adaptive process while addiction is compulsive medication abuse despite negative effects.
Healthcare providers closely monitor patients while they take the drug. Gradual dose tapering may be recommended when stopping therapy is required. The patient mustn't cease regular tapentadol therapy independently of the healthcare provider.
